What is CBD (cannabidiol)?

06/11/2023
Chemical structure of CBD (Cannabidiol)

CBD (cannabidiol) has become one of the most widely studied cannabinoids found in the cannabis plant. Recognised for its distinct characteristics compared to THC, CBD is non-intoxicating, although it can affect the brain, and continues to attract significant scientific interest.

Its non-intoxicating profile has contributed to its growing presence in research discussions and product development across various sectors.

Research efforts are helping to clarify how CBD differs from other cannabinoids and what makes it a prominent area of study within the broader cannabis plant profile.

Understanding the unique properties of CBD remains important for those seeking accurate and reliable information. As interest in cannabinoids continues to expand, maintaining a clear and well-researched perspective on compounds such as CBD is essential for supporting informed discussions and responsible developments in the field.

Close-up view of cannabis leaves in black background

Key takeaways

  • CBD is non-intoxicating, although it can affect the brain.
  • It is available in various formats such as extracts, vaporised liquids, capsules and topicals.
  • Scientific studies continue to investigate its characteristics and applications.
  • Product transparency and batch testing help support quality and trust.
  • CBD may cause mild side effects and could interact with certain substances.

This article is provided for informational purposes only and does not relate to any of the products available in our online shop. For more information, please see our full disclaimer.

What is CBD oil?

The origins and discovery of CBD

CBD (cannabidiol) was first identified in 1940 by American chemist Roger Adams, who successfully isolated the compound from the cannabis plant. Although Adams was able to extract CBD, the full structure and characteristics of the cannabinoid were not fully understood until several years later, when further research clarified its non-intoxicating nature compared to THC.

Since its discovery, CBD has become a key focus in scientific studies exploring the complexity of the cannabis plant. Notably, a 2011 review published in the British Journal of Clinical Pharmacology outlined CBD’s diverse pharmacological profile, highlighting its growing importance in cannabinoid research.

Research efforts continue to deepen understanding of CBD's interactions with the body's natural systems and its distinct role among cannabis-derived compounds.

CBD has gained increasing recognition as a non-intoxicating compound derived from the cannabis plant. Unlike THC, CBD does not produce intoxicating effects, and its distinct characteristics have made it a subject of growing interest within scientific research.

Extracted primarily from Cannabis sativa, CBD is now incorporated into a variety of products across different sectors. As research continues to expand, interest in understanding CBD’s role among the many compounds found in the cannabis plant remains strong.

Prefer watching over reading? This video covers the key points from the article:

What is the difference between CBD and THC?

Different forms of CBD products

CBD is incorporated into a variety of product types, including oils, extracts, vaporised liquids, capsules and topicals. These different forms offer options for individuals who wish to choose a format that aligns with their preferences and routines.

From my experience following cannabinoid research at Formula Swiss, I have observed the increasing diversification of CBD product formats over recent years. CBD oils remain among the most widely recognised forms, while extracts offer a more concentrated format for various applications.

Vaporised liquids and capsules provide alternative options, and topicals are intended for external application to the skin.

CBD oil, CBD cream and CBD lotion on white table
Form Advantages Disadvantages
Oils Familiar and widely available May have a strong aroma or taste
Extracts Highly concentrated Can be more expensive
Vaporised liquids Alternative format Requires specialised equipment
Topicals Applied externally to targeted areas Surface application only

Buy CBD oils with less than 0.2% THC here

CBD in beauty and skincare

CBD (cannabidiol) has gained increasing attention within the beauty and skincare sector for its inclusion in a wide range of topical formulations. CBD is now featured in products intended for external use across cosmetics, skincare and personal care ranges.

CBD-based formulations include facial serums, creams, cleansers, toners, body lotions and oils. These products are designed to align with broader skincare routines and are applied topically. CBD is also featured in bath products, hair care and massage oils, reflecting its growing role in the beauty industry.

While CBD has become increasingly visible in beauty and personal care products, it is important to be aware of potential side effects and possible interactions with other substances. A cautious approach and professional guidance can support informed decisions about incorporating CBD into personal routines.

Opened CBD cream with CBD leaves on top

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The endocannabinoid system (ECS)

The endocannabinoid system (ECS) is a cell-signalling network in the body, and researchers study how CBD interacts with it.

How CBD interacts with the endocannabinoid system

To understand that research, it helps to look more closely at the endocannabinoid system:

  • CB1 receptors are primarily found in the brain and central nervous system and are associated with regulating mood, memory and the perception of pain.
  • CB2 receptors are mainly found in the immune system and are involved in regulating inflammation and immune responses.

CBD’s mechanisms cannot be reduced to a general claim that it increases endocannabinoid production or restores balance. Research in experimental cell models found that CBD could modify signalling at CB1 receptors. Such findings help investigate molecular activity, but do not establish predictable benefits from a particular CBD product in people.

What is the endocannabinoid system?

Purity and content accuracy in CBD products

Ensuring product purity and content accuracy remains important for maintaining quality and safety standards. Reviewing transparency measures and batch testing is essential when considering different cannabinoid-based products.

Detailed information about our laboratory testing procedures and product certifications is available in our quality report.

Reputable manufacturers typically provide certificates of analysis to verify the CBD content and screen for potential contaminants. Such transparency helps to confirm that product labelling accurately reflects the content, supporting informed decision-making.

The amount of CBD present in products can vary. By prioritising the purity and content accuracy of CBD products, individuals can make more informed decisions and select products that align with their preferences.

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CBD products

Advances in the scientific study of CBD

Scientific research into CBD continues to expand, examining its potential interactions with various biological systems. Areas of study include neurological functions, mood regulation, inflammation and related complex processes. Investigations are being conducted globally to assess both the safety and mechanisms of cannabidiol under controlled conditions.

One area of particular focus is CBD in relation to epilepsy. A prescription formulation containing CBD has been approved by the U.S. Food and Drug Administration (FDA) for rare forms of epilepsy, based on specific clinical findings.

A systematic review in Experimental Neurology examined available data on CBD's role in treatment-resistant epilepsy, particularly in paediatric cases.

Scientists doing research on CBD in a farmResearchers have also studied how CBD may interact with the body’s systems involved in mood regulation. Preliminary investigations, primarily in animal models, have identified activity in receptors associated with serotonin signalling. Institutions such as the National Institute of Mental Health have acknowledged the growing research interest, while stressing the need for larger-scale clinical trials.

In the context of pain-related studies, early-stage research has assessed CBD’s potential influence on inflammatory pathways and neurotransmitter function. Reviews, including one in the journal Neurotherapeutics, have discussed the current status of cannabinoid-based research, while also noting the limited number of high-quality human trials to date.

Studies on neurodegenerative conditions such as Alzheimer's disease and Parkinson's disease are also ongoing. Early findings, mainly from preclinical models, have suggested that CBD may affect markers of oxidative stress and inflammation. However, these results remain preliminary and require validation through comprehensive human research.

Scientist examining CBD leaves

Making informed choices about CBD

In my experience following cannabinoid research at Formula Swiss, making informed decisions about CBD begins with evaluating product transparency, quality and potential interactions.

Reputable brands that provide batch certificates of analysis, detailed sourcing information and clear manufacturing practices offer greater assurance of product consistency and integrity. You can review our quality report for detailed information about our testing procedures and product certifications.

Understanding the content and formulation of CBD products is equally important. Attention to the possibility of interactions between CBD and other substances, such as anticoagulants or neurological treatments, should not be overlooked.

By carefully considering these factors, individuals can make informed choices about CBD products, ensuring that decisions align with personal circumstances and broader safety standards.

Consider consulting healthcare professional when making choices about CBD

Personal perspective

Based on my experience following cannabinoid research at Formula Swiss, I have observed the growing scientific focus on CBD.

CBD’s non-intoxicating nature and distinct characteristics compared to THC have made it a prominent subject of study across a variety of sectors, including wellness, food and skincare.

It is encouraging to see research efforts expanding globally, with careful exploration of CBD’s interactions at the biological level and increasing attention to ensuring product transparency and quality standards.

Understanding the unique properties of CBD remains essential for supporting informed discussions and responsible development within the cannabinoid industry.

In my experience, upholding a focus on reliable information, scientific evidence and adherence to industry standards remains essential as public interest in CBD continues to grow.

By encouraging thoughtful engagement with research findings and responsible communication, the industry can help ensure that CBD’s potential is explored with clarity and integrity.

Get our CBD oil with less than 0.2% THC here

Frequently asked questions

What is CBD?

CBD, short for cannabidiol, is one of at least 113 identified cannabinoids found in the hemp plant. It is a naturally occurring compound used in a variety of products, including oils and topical formulations. CBD is studied for its interactions with the body's natural systems.

Can you get “high” from CBD?

CBD does not cause the characteristic intoxication or “high” associated with THC (tetrahydrocannabinol). Non-intoxicating does not mean that CBD has no effect on the brain or that a product containing it is free of risks.

Is CBD oil safe or addictive?

CBD is not associated with the characteristic intoxicating effects linked to THC. However, individual responses can vary, and consultation with a qualified healthcare professional is advisable when considering CBD products.

Our guide to CBD side effects explains what studies have reported and who should be careful.

Are CBD oil and hemp seed oil the same thing?

No, they are different. CBD oil is extracted from the flowers, leaves and stalks of the hemp plant and contains cannabinoids such as CBD. Hemp seed oil is extracted from hemp seeds and typically contains minimal cannabinoid content.

How and where is CBD grown and harvested?

CBD is extracted from hemp plants that are specifically cultivated to contain low amounts of THC while yielding higher concentrations of CBD. These plants are grown following agricultural practices aimed at maintaining product quality and meeting established industry standards.

What is the difference between hemp and marijuana?

Hemp and marijuana are terms used for cannabis with different THC characteristics and uses. Hemp is generally defined by a low THC limit under the applicable jurisdiction’s rules; this does not mean that every hemp plant has a high CBD concentration. The cultivar and measured cannabinoid content matter, and legal definitions vary between jurisdictions.

How are CBD extracts made?

CBD extracts are produced using methods that separate cannabinoids from the hemp plant. Common techniques include CO2 extraction, which uses pressurised carbon dioxide, and ethanol extraction, which uses alcohol-based solvents. Each method can influence the final product's composition and purity.

What is the difference between CBD and THC?

CBD (cannabidiol) and THC (tetrahydrocannabinol) are distinct cannabinoids. CBD is non-intoxicating, although it can affect the brain. THC is recognised for producing the characteristic “high” associated with cannabis use. Their biological activity differs, and research into either compound should not be taken as proof of a particular product’s effects or suitability.


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Robin Roy Krigslund-Hansen

Robin Roy Krigslund-Hansen

About the author

Robin Roy Krigslund-Hansen is the co-founder and CEO of Formula Swiss and is responsible for formulation. Since co-founding the company in 2013, he has written about hemp, CBD, and the cannabis industry. His perspective draws on building Formula Swiss, conversations with researchers, and supporting CBD research.

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