Can CBD help cope with stress and depression?

by Formula Swiss June 02, 2019 4 min read

Can CBD help cope with stress and depression?

Stress and depression is the most common mood disorder. Nearly 350 million people are suffering from depression across the globe. Yet there are many therapies and medications to cope with stress and anxiety, but people are also finding the medical benefits of CBD to be effective in dealing with stress and depression. CBD also has many other benefits but the research in this regard is still very small and more studies should be conducted in order to conclusively prove the medicinal advantages of CBD.

Researches suggest that by stress and depression the receptors and neurotransmitters of the endocannabinoid system become weak and ineffective. CBD acts as the external receptor in our endocannabinoid system that helps the internal receptors to restore its functions and controls, it strengthens the receptors. These receptors play a role in the motor control, emotions, behaviour and cognition. It affects the emotional responses of the person, so optimal working of the endocannabinoid system is crucial for the prevention of stress and anxiety.

Can CBD affect stress and depression?

There are many studies available revealing the effects of CBD on stress and depression. From the research done in these studies, we can conclude to some extent that CBD can help with coping stress and depression. A study conducted in 2010 suggested that CBD has the ability to reduce the symptoms of anxiety in people with a social anxiety disorder (SAD). In this study, it was stated that the brain scans of people show that the blood flow to the regions which are linked to anxiety was altered. Not only the patients felt better with CBD but also the way their brain responded to anxiety was changed.

A study published in 2014 stated that CBD oil has anti-depressant and anti-anxiety effects in an animal-based model. Another 2015 research found that CBD can be a helping hand in a number of anxieties including panic disorder, social anxiety disorder, generalized anxiety disorder, post-traumatic stress disorder and obsessive-compulsive disorder. The report also concluded that long-term use of CBD is not researched, however for short-term anxiety disorders CBD can effectively provide positive results while it can also be used in a prolonged course.

A 2016 study considered the effects of CBD on post-traumatic stress disorder and stress-provoked sleep in a patient with the history of trauma. It was revealed that the child’s anxiety was reduced and stress-provoked insomnia was also relieved. In another study, researchers made the patients suffering from Social Anxiety Disorder perform a public speaking test. It was concluded that CBD reduced discomfort, anxiety and cognitive impairment in their speech performance.

Due to the fact that most research done on CBD regarding its ability to manage stress and anxiety is done on animals and laboratory. There are no significant studies based on humans, so it cannot be effectively concluded that it will provide the same results on humans as it provides on animals. However, the laboratory testing and animal-based testing provide an insight into the potential and possible outcome of CBD.

How CBD works

CBD acts as the 5-HT1A agonist, 5-HT1A is a type of serotonin receptor which is responsible for managing anxiety and depression and stress can be dealt with with medications that target the serotonin system. The increase in the availability of serotonin in the synaptic space leads the brain cells to transmit more serotonin signals which help in reducing anxiety and stress. An animal study shows that CBD also helps in the production of serotonin by enhancing 5-HT1A transmission and boosting signals.

CBD is also used in the regeneration of the neurons that are helpful in reducing stress and depression. The brain scans of people suffering from depression show less hippocampus which is responsible for memory and cognition formation. Depression can be controlled and reduced by the formation of new neurons in the hippocampus which is referred to as neurogenesis. An animal study revealed that regular administration of CBD helps in developing neurons in the hippocampus which is helpful in dealing with anxiety and depression.

Other than that CBD is an effective dietary supplement to support the endocannabinoid system to keep its functioning on the optimal level. The central nervous system is also a part of the endocannabinoid system and the receptors are available in large number in the brain so the ECS must function and control all the vital processes effectively so that stress and anxiety are released.

How to use CBD for stress

CBD can be used in the form of supplements or CBD oil is used sublingually, however, in order to administer results from CBD, it is vital to consider a regular use of CBD. The dosage and quantity of CBD also play a crucial role in order to achieve desired benefits from CBD. The product that uses for CBD, must have a good content of CBD extracted from the hemp plant and does not contain any THC elements. If regular consumption of CBD still does not provide any positive effects on your stress and depression, then you may want to increase the dosage and check it over a period of time in order to see benefits.

Final thoughts

Though a little piece of research is available on the procedures of overcoming stress and depression by the consumption of CBD, the research still is very admiring. It can be stated that CBD has an effect on the stress and anxiety and can help in reducing the symptoms. However, it can only be proven by giving the stress patients CBD and regular administration of CBD is necessary. Many people get benefitted from CBD in dealing with various diseases, however, some have also reported that CBD increases the stress and anxiety but no scientific evidence is available in this regard.

CBD has become the most popular topic in order to cope with various diseases. It does provide many benefits, therefore it has become legalized in many countries. Proper use of CBD will lead to an effective endocannabinoid system which regulates all the processes of the body.


This article was written by an independent and third-party author specialising in CBD, hemp and cannabis research. Any opinion, advice or recommendation expressed in the article does not reflect the opinion of Formula Swiss AG or any of our employees. We do not make any claims about any of our products and refer to our disclaimer for more information.

Formula Swiss
Formula Swiss

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